https://en.ikswiki.in/index.php?action=history&feed=atom&title=Draft%3ASaumya_Test_file_2_text_1supplDraft:Saumya Test file 2 text 1suppl - Revision history2026-11-09T11:59:37ZRevision history for this page on the wikiMediaWiki 1.40.0https://en.ikswiki.in/index.php?title=Draft:Saumya_Test_file_2_text_1suppl&diff=1795&oldid=prev172.20.170.28: spacing2026-06-16T12:01:43Z<p>spacing</p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:31, 16 June 2026</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Strengthening Near-to- Home Management of Possible Serious Bacterial Infection (PSBI) in Sick Young Infants (0-59 Days) When Referral is Not Feasible: An Implementation Research Study in a Rural Block of''' '''Kanpur District, Uttar Pradesh (India)'''</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Strengthening Near-to- Home Management of Possible Serious Bacterial Infection (PSBI) in Sick Young Infants (0-59 Days) When Referral is Not Feasible: An Implementation Research Study in a Rural Block of''' '''Kanpur District, Uttar Pradesh (India)'''</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Introduction:'''</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Introduction:'''</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Globally, 2.3 million newborn lives ended in the first month of life, accounting for almost half of the under-five deaths ([https://data.unicef.org/topic/child-survival/neonatal-mortality/ <u>ref</u>], [https://data.worldbank.org/indicator/SH.DYN.NMRT?locations=1W&name_desc=false <u>ref</u>] ). <span class="mark">Despite a</span> considerable decline in under-5 mortality <span class="mark">([https://data.unicef.org/topic/child-survival/under-five-mortality/ <u>ref</u>])</span>, the reduction of neonatal mortality remains sluggish posing a challenge to the LMIC’s target of achieving the SDG goal (3.2) of “ending preventable deaths of newborns by 2030, with all countries aiming to reduce neonatal mortality below 12 per 1000 live births”. ([https://sdgs.un.org/goals/goal3#targets_and_indicators <u>ref</u>], ref?). <span class="mark">Amidst the largest number of neonatal deaths (</span>39%) occurring in Southern Asia, <span class="mark">India stands to be one in the five countries that account for half of all newborn deaths (UNICEF, 2017 (2)([https://data.unicef.org/resources/levels-and-trends-in-child-mortality-2024/ <u>ref</u>], [https://www.unicef.org/media/89226/file/The%20State%20of%20the%20World%27s%20Children%202012.pdf <u>ref</u>]).</span></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Globally, 2.3 million newborn lives ended in the first month of life, accounting for almost half of the under-five deaths ([https://data.unicef.org/topic/child-survival/neonatal-mortality/ <u>ref</u>], [https://data.worldbank.org/indicator/SH.DYN.NMRT?locations=1W&name_desc=false <u>ref</u>] ). <span class="mark">Despite a</span> considerable decline in under-5 mortality <span class="mark">([https://data.unicef.org/topic/child-survival/under-five-mortality/ <u>ref</u>])</span>, the reduction of neonatal mortality remains sluggish posing a challenge to the LMIC’s target of achieving the SDG goal (3.2) of “ending preventable deaths of newborns by 2030, with all countries aiming to reduce neonatal mortality below 12 per 1000 live births”. ([https://sdgs.un.org/goals/goal3#targets_and_indicators <u>ref</u>], ref?). <span class="mark">Amidst the largest number of neonatal deaths (</span>39%) occurring in Southern Asia, <span class="mark">India stands to be one in the five countries that account for half of all newborn deaths (UNICEF, 2017 (2)([https://data.unicef.org/resources/levels-and-trends-in-child-mortality-2024/ <u>ref</u>], [https://www.unicef.org/media/89226/file/The%20State%20of%20the%20World%27s%20Children%202012.pdf <u>ref</u>]).</span></div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote><span class="mark">Sepsis &amp; infections contribute to 35% of neonatal deaths in South Asia, making it the second major contributing cause of neonatal mortality after prematurity ([https://data.unicef.org/resources/levels-and-trends-in-child-mortality-2024/ <u>ref</u>]</span>, <span class="mark">[https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(18)30385-1/fulltext <u>ref</u>], [https://www.unicef.org/media/77166/file/Ending-preventable-newborn-deaths-and-stillbirths-by-2030-universal-health-coverage-in-2020%E2%80%932025.pdf <u>ref</u>]). The recommended management for sepsis and infection is inpatient treatment, however, in resource-constrained settings, accessing specialized care in higher facilities and longer hospital admission remains challenging (Ref). Large field trials from Africa and Asia demonstrated the efficacy of simplified antibiotic treatment for young infants with sepsis, and infections, broadly grouped under the syndromic category of Possible Serious Bacterial Infection or PSBI, in an outpatient setting. Building on the evidence, World Health Organization (WHO), in 2015, recommended</span> that PSBI should be managed with a 7 days simplified antibiotic regimen ([https://doi.org/10.3329/jhpn.v29i3.7873 <u>ref</u>], [https://doi.org/10.1016/S2214-109X(14)70347-X <u>ref</u>], [https://doi.org/10.1016/S2214-109X(16)30335-7 <u>ref</u>]) on an outpatient basis when referral to higher facilities is not feasible ([https://journals.lww.com/pidj/abstract/2012/07000/community_based_treatment_of_serious_bacterial.2.aspx <u>ref</u>], [https://doi.org/10.1016/S0140-6736(99)03046-9 <u>ref</u>], [https://pubmed.ncbi.nlm.nih.gov/18539225/ <u>ref</u>], [https://journals.lww.com/jfmpc/pages/default.aspx <u>ref</u>], [https://doi.org/10.5555/uri:pii:S0140673696908569 <u>ref</u>], [https://doi.org/10.3329/jhpn.v29i3.7873 <u>ref</u>]). This further contextualized in broader Integrated Management of Newborn and Child Illness or IMNCI guideline that <span class="mark">provides a tool for non- specialists to systematically classify , identify treatment and manage various morbidities</span> <span class="mark">amongst children upto 5 years of age</span>.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><blockquote><span class="mark">Sepsis &amp; infections contribute to 35% of neonatal deaths in South Asia, making it the second major contributing cause of neonatal mortality after prematurity ([https://data.unicef.org/resources/levels-and-trends-in-child-mortality-2024/ <u>ref</u>]</span>, <span class="mark">[https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(18)30385-1/fulltext <u>ref</u>], [https://www.unicef.org/media/77166/file/Ending-preventable-newborn-deaths-and-stillbirths-by-2030-universal-health-coverage-in-2020%E2%80%932025.pdf <u>ref</u>]). The recommended management for sepsis and infection is inpatient treatment, however, in resource-constrained settings, accessing specialized care in higher facilities and longer hospital admission remains challenging (Ref). Large field trials from Africa and Asia demonstrated the efficacy of simplified antibiotic treatment for young infants with sepsis, and infections, broadly grouped under the syndromic category of Possible Serious Bacterial Infection or PSBI, in an outpatient setting. Building on the evidence, World Health Organization (WHO), in 2015, recommended</span> that PSBI should be managed with a 7 days simplified antibiotic regimen ([https://doi.org/10.3329/jhpn.v29i3.7873 <u>ref</u>], [https://doi.org/10.1016/S2214-109X(14)70347-X <u>ref</u>], [https://doi.org/10.1016/S2214-109X(16)30335-7 <u>ref</u>]) on an outpatient basis when referral to higher facilities is not feasible ([https://journals.lww.com/pidj/abstract/2012/07000/community_based_treatment_of_serious_bacterial.2.aspx <u>ref</u>], [https://doi.org/10.1016/S0140-6736(99)03046-9 <u>ref</u>], [https://pubmed.ncbi.nlm.nih.gov/18539225/ <u>ref</u>], [https://journals.lww.com/jfmpc/pages/default.aspx <u>ref</u>], [https://doi.org/10.5555/uri:pii:S0140673696908569 <u>ref</u>], [https://doi.org/10.3329/jhpn.v29i3.7873 <u>ref</u>]). This further contextualized in broader Integrated Management of Newborn and Child Illness or IMNCI guideline that <span class="mark">provides a tool for non- specialists to systematically classify , identify treatment and manage various morbidities</span> <span class="mark">amongst children upto 5 years of age</span>.</div></td></tr>
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